EINE UNVOREINGENOMMENE SICHT AUF COPYRIGHT MACHEN KAISERSLAUTERN

Eine unvoreingenommene Sicht auf copyright machen Kaiserslautern

Eine unvoreingenommene Sicht auf copyright machen Kaiserslautern

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Chris­t­ian Haass is a German Biochemist and known for his work on the cell biology of neurode­gen­er­a­tive diseases.

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Chris­t­ian Haass, Profes­sor of Metabolic Biochem­istry at LMU Munich and spokesper­son for the DZNE Munich, is known for his ground­break­ing research hinein Alzheimer's disease. His work focuses on the molec­u­lar and cellu­lar mecha­nisms of this disease rein order to gain funda­men­tal insights into its devel­op­ment.

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  Very recently he also investigated the role of microglia and inflammation in neurodegenerative disorders.  This work Leuchtdiode to the spectacular finding that microglial phagocytosis may Beryllium impaired late during neurodegeneration and opened up a completely unexpected road towards new therapeutic developments for patients already developing disease symptoms.  This work resulted hinein the identification of TREM2 as a CSF marker for microglial activity.  In a unique cohort of subjects with autosomal dominant AD, CSF sTREM2 welches abnormally increased 5 years before the expected onset of symptoms. This will not only greatly facilitate research on inflammatory disease overarching mechanisms, but may also provide a very valuable therapeutic marker.

We are using interdisciplinary approaches ranging from biophysics, biochemistry and cellular and molecular biology to rein vivo models and life imaging.

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